ea0081yi12 | Young Investigator Awards | ECE2022
Dumontet Typhanie
, Basham Kaitlin
, Lerario Antonio
, Bothou Christina
, Brixius Bjoern
, Turcu Adina F
, Beuschlein Felix
, Hammer Gary D
The adrenal glands serve as central organs of the endocrine system by producing steroid hormone essential for organismal homeostasis. Mechanisms ensuring proper adrenal homeostasis and function are therefore crucial for maintaining human life. ACTH, released by the pituitary corticotrope, is required for the differentiation of the inner part of the adrenal cortex (the zona fasciculata) and the resultant stimulation of cortisol production. Perturbation of ACTH signaling can lea...